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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASR
All Species:
14.55
Human Site:
T868
Identified Species:
40
UniProt:
P41180
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41180
NP_000379.2
1078
120674
T868
L
F
K
P
S
R
N
T
I
E
E
V
R
C
S
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
C640
R
Q
A
L
F
P
L
C
F
T
I
C
I
S
C
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
C640
R
Q
A
L
F
P
L
C
F
T
I
C
I
S
C
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY96
1079
120821
T868
L
F
K
P
S
R
N
T
I
E
E
V
R
S
S
Rat
Rattus norvegicus
P48442
1079
120849
T868
L
F
K
P
S
R
N
T
I
E
E
V
R
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515899
1088
120096
T868
L
F
K
P
A
R
N
T
I
E
E
V
R
C
S
Chicken
Gallus gallus
XP_416491
1059
118051
Y857
C
I
F
F
N
K
V
Y
I
I
L
F
K
P
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
L668
M
N
F
E
L
K
E
L
L
C
M
L
Y
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
K777
D
R
R
E
V
I
L
K
C
K
I
Q
D
M
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
25.7
N.A.
N.A.
93.6
93.6
N.A.
81.9
85.4
N.A.
30.6
N.A.
26.8
N.A.
N.A.
N.A.
Protein Similarity:
100
43.5
43.4
N.A.
N.A.
96.8
96.9
N.A.
87.8
90.5
N.A.
47.5
N.A.
46.2
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
N.A.
N.A.
93.3
93.3
N.A.
93.3
13.3
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
0
N.A.
N.A.
93.3
93.3
N.A.
100
33.3
N.A.
26.6
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
12
0
0
0
0
0
0
23
12
12
0
23
0
23
23
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
23
0
0
12
0
0
45
45
0
0
0
0
% E
% Phe:
0
45
23
12
23
0
0
0
23
0
0
12
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
12
0
0
56
12
34
0
23
0
0
% I
% Lys:
0
0
45
0
0
23
0
12
0
12
0
0
12
12
0
% K
% Leu:
45
0
0
23
12
0
34
12
12
0
12
12
0
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
12
0
0
12
0
% M
% Asn:
0
12
0
0
12
0
45
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
45
0
23
0
0
0
0
0
0
0
12
12
% P
% Gln:
0
23
0
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
23
12
12
0
0
45
0
0
0
0
0
0
45
0
0
% R
% Ser:
0
0
0
0
34
0
0
0
0
0
0
0
0
45
67
% S
% Thr:
0
0
0
0
0
0
0
45
0
23
0
0
0
0
0
% T
% Val:
0
0
0
0
12
0
12
0
0
0
0
45
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _